Role of Antidiuretic Hormone in Hyponatremia in Patients with Isolated Adrenocorticotropic Hormone Deficiency.

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Role of antidiuretic hormone in hyponatremia in patients with isolated adrenocorticotropic hormone deficiency.

We found symptomatic hyponatremia in four elderly patients in which serum sodium (Na) levels ranged from 101 to 122 mEq/l. All 4 patients had low levels of plasma adrenocorticotropic hormone (ACTH), serum cortisol, and urinary excretion of 17-OHCS, and poor responses of ACTH to exogenous insulin and antidiuretic hormone (ADH). Other pituitary hormones were all normal. They were therefore diagno...

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Adrenocorticotropic action of antidiuretic hormone.

By means of direct arterial perfusion of the adrenal glands of the hypophysectomized dog, it has been shown that synthetic lysine, arginine and acetyl arginine vasopressins stimulate the adrenal cortex directly to secrete hydrocortisone. Pressor activity and cortisol-stimulating activity were demonstrated to be independent of each other. Similar polypeptides, such as oxytocin, insulin, glucagon...

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Adrenocorticotropic Action of Antidiuretic Hormone

By means of direct arterial perfusion of the adrenal glands of the hypophysectomized dog, it has been shown that synthetic lysine, arginine and acetyl arginine vasopressins stimulate the adrenal cortex directly to secrete hydrocortisone. Pressor activity and cortisol-stimulating activity were demonstrated to be independent of each other. Similar polypeptides, such as oxytocin, insulin, glucagon...

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[A case of isolated adrenocorticotropic hormone (ACTH) deficiency associated with severe hyponatremia and an empty sella].

概要 症例 は56才,男 性.54才 時 よ り食欲不 振が 出現,昭 和59年,低Na血 症 にて入院.昭 和60 年4月 よ り悪 心,嘔 吐 出現 し当科 紹介.血 清Naの 最低値は105mEq/1.血 中コ ルチ ゾール,尿 中17-OHCSの 著 しい基 礎低値.血 漿ACTH基 礎 値 は測定 感度 以下 で,イ ンス リン低 血糖, L8-V,CRFに 無反 応.他 の下垂体前 葉ホル モ ン正常.ACTH単 独 欠損症 と診 断,画 像診 断上empty sellaが確認 された.低Na血 症下 のACTH-Z負 荷 にてコルチ ゾール,17-OHCSLは 増加 し,自 由 水 ク リア ラ ンス は一0.85~ 一0.95m1/分 よ りほぼ0に 至 り,低Na血 症 は改善, ADHは1.4→0.5 pg/mlと 低下 した.本 例 の低Na血 症 に はグルコ...

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Petrified Ear Auricles with Isolated Adrenocorticotropic Hormone Deficiency

A 22-year-old man was hospitalized with nausea. His serum sodium, adrenocorticotropic hormone (ACTH), and cortisol levels were 108 mmol/L (range, 138-145), 2.2 pg/mL (range, 7.2-63.3), and 0.08 μg/dL (range, 4.64-24.56), respectively. The levels of other anterior pituitary hormones were as follows: growth hormone 2.46 ng/mL (range, 0.663.68), thyroid-stimulating hormone 0.625 μIU/mL (range, 0.5...

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ژورنال

عنوان ژورنال: Endocrinologia Japonica

سال: 1991

ISSN: 0013-7219,2185-6370

DOI: 10.1507/endocrj1954.38.325